It is a common pattern in pipelines (and Spider middlewares as well) to use Spider attributes to decide what to do:
class MyPipeline:
def process_item(self, item, spider):
if getattr(spider, 'my_pipeline_enabled', False):
# faz a coisa aqui
This way, although the pipeline is enabled in the entire project, you can use the attribute my_pipeline_enabled
to enable the pipeline only for the Spiders you want.
You can also expand this code to consider a configuration if needed.
In Scrapy 0.25+ (not yet released, so far only taking Git Change), you also have the alternative of using settings in Pider that take precedence over those in the project.