In the tags you indicate that your doubt is related to Bootstrap 3. So you need to understand the concept of grid Examples to solve your question. Other concepts are margin and padding, but the grid is the most important here.
I also assumed that you have some knowledge of creating non-responsive websites.
And that’s the problem.
After 15 years making websites with <table> and then with the CSS before CSS3, I also had a hard time understanding things like this.
I noticed that you speak in columns below each other... Columns are next to each other. Lines are below each other.
In bootstrap you nest columns within rows.
<div class="row">
<div class="col-md-4">coluna 4/12 = 1/3</div>
<div class="col-md-4">coluna 4/12 = 1/3</div>
<div class="col-md-4">coluna 4/12 = 1/3</div>
</div>
<div class="row">
<div class="col-md-3">.coluna 3/12 = 1/4</div>
<div class="col-md-4">coluna 4/12 = 1/3</div>
<div class="col-md-5">coluna 5/12</div>
</div>
This code creates two rows, each with three columns.
The first row has 3 columns of the same width, each one a third the size.
The second row also has 3 columns. each with a different size.
Did you notice that I divided it by 12? It’s because the grid of bootstrap does this. It divides the width of the screen into 12 parts.
You must have noticed the md. This is a class modifier that indicates that this rule applies to medium monitors (think tablet) up.
That is to say col-md-3, can be read as occupy a room (3/12=1/4) if device screen is average.
Now, think about mobile first, because bootstrap rules are applied from bottom to top (in terms of size).
If you use col-sm-7 will be saying occupy 7 spaces 12, when the screen is small.
So do not set absolute or percentage sizes for div. Understand the grid and adapt the site layout to use it.
In responsive design, you can create a layout version for each screen size (old-fashioned, frameworks like boostrap) and have the biggest headache to keep things going. Or you can better understand the concept and make a single code for any device.
Concepts to be studied: grid, margin and padding.
Boostrap website in Portuguese